Nootropics, smart drugs, and cognitive enhancers are a new wave of drugs that can boost brain memory function. The human brain as an organ is proven to have unimaginable capabilities. It can process, learn, and store limitless amounts of information. These nootropics help the process.

This article will cover the best nootropics and smart drugs available in the world today. The different types of nootropics and smart drugs will also be discussed.

The Best Brain Boosting Drugs

Mind Lab Pro


  • Complete natural remedy with no stimulants
  • Users can purchase it from anywhere in the world
  • Money-back guarantee
  • Suitable for persons of every age
  • Boosts brain power and cognitive performance


  • Doesn't work well with other nootropic stack
  • Expensive

The first and likely the most potent smart drug on the list is Mind Lab Pro manufactured by Opti-Nutra. After the first Mind Lab Pro brain pill was created in 2015, the brand has seen several additions to the ingredients list to beef up the effectiveness.

The ingredients list for the latest version includes:

  • Citicoline
  • Vitamin B6
  • Phosphatidylserine
  • Rhodiola Rosea
  • Vitamin B9
  • Lion’s mane mushroom
  • Maritime pine bark extract
  • Bacopa Monnieri
  • L-theanine and L-tyrosine
  • Vitamin B12

Mind Lab Pro is able to target six brain pathways; brain chemicals, blood flow, brain waves, neuroprotection, neuroregeneration, and energy to help boosts memory, performance, structural performance, and mindset. All these benefits makes the product excellent for people who want to tap into their creative side and improve memory retention ability, with effects that lasts for about 6-8 hours. Opti-Nutra recommends that users take a maximum of two Mind Lab Pro pills either in the morning or early in the afternoon.

Performance Lab


  • Money-back guarantee
  • 24/7 customer service
  • 0% GMO, it is gluten-free, and it contains no caffeine, no artificial preservatives, no coloring, and no synthetic additives.
  • Anti-doping agency banned substances are not included.


  • Can only be purchased via the official website
  • No vitamins present, so it needs to be taken with multivitamins
  • Daily intake might be costly

The Performance Lab brain supplement is without a doubt one of the best premade nootropic supplements that hits the nail on the head with just four ingredients:

  • Sharp PS Green
  • Cognizin (citicoline)
  • L-Tyrosine
  • Maritime Pine Bark Extract

This product is well known for its ability to solve significant problems relating to brain aging. Due to its very few ingredients list, it can be stacked with several other brain function supplements. Additionally, people with dietary restrictions have nothing to worry about since this drug is gluten-free, soy-free, and GMU free.

Lastly, users looking to improve cognitive function can expect about 5-7 hours of focus. It also speeds up the brain recovery process.



  • Money-back guarantee
  • Only natural ingredients are mixed
  • Zero side effects


  • Can only be purchased via the official website

From one of the best nootropic supplements manufacturers in the game called Wolfson Berg Limited, comes the Noocube. Noocube is not only affordable but can also be purchased from anywhere in the world. The Noocube contains seven unique ingredients proven to increase brain health, mental performance, and the ability to multitask.

The ingredients list includes:

  • Huperzine A
  • Cat's Claw
  • Bacopa Monnieri
  • Resveratrol
  • Alpha glycerylphosphorylcholine (Alpha GPC)
  • Pterostilbene
  • L-theanine & L-tyrosine

All of these combined give the Noocube its special brain-boosting effect.

Manufacturers recommend that users take about two capsules of Noocube every morning during breakfast. After 30-45 minutes, the user will begin to feel the effects of the Noocube. These effects will only wear off after 8-10 hours. 

Another point worth mentioning is that one container of the Noocube contains 60 tablets, which means one month supply of smart pills for the user.

Individual Natural Nootropic Ingredients & Uses

Here is a list comprising 10 different natural nootropic ingredients.

1. Bacopa Monnieri

The Bacopa Monnieri extract comes from the Brahmi plant. This extract is known to contain bacosides; that help to repair damaged neurons. 

As an ancient plant, it has long been used to improve memory processing and enable users to develop a faster reaction rate. The plant hastens dendrites' production in the human body, which means these nerve cells will receive information quicker.

Bacopa Monnieri is also used to treat anxiety, insomnia and it is used as an anti stroke and anticonvulsant agent. Additionally, it can as well improve cognitive function and hand coordination. After taking the Bacopa Monnieri, it might take a while before the effects are felt; this ranges from one user to another.

To achieve the full effect of the Bacopa Monnieri, combine it with phosphatidylserine and citicoline; this way, the effectiveness of this nootropic stack is increased.

2. Ginkgo Biloba

For people looking to remain very calm in tight situations, the Ginkgo Biloba is the right herb. 

This herb has been known to the Chinese for years and is well known for its ability to improve blood flow to the brain, concentration, and brain aging. It also has antioxidant abilities. Older adults who are slowly or rapidly losing control over their cognitive function will find this drug very useful.

To increase the effectiveness of the Ginkgo Biloba, it is combined with Bacopa Monnieri, citicoline, and phosphatidylserine to make it the best nootropic stack. It is also useful in the cardiovascular system to improve blood flow to the brain so that the brain gets enough oxygen.

3. Lion's mane Mushroom

As the name says, Lion's mane mushroom is a readily available and consumable mushroom packed by many health stores. 

This natural nootropic supplement is not only capable of boosting brain functions and giving the brain cells regenerative abilities, it can also be used to prevent cancer. Physicians recommend its use in treating Alzheimer's and for improving overall brain health.

All these benefits of the Lion’s mane Mushroom is possible due to the presence of compounds in the mushroom that guarantee new brain cell growth. These compounds are capable of inducing the production and growth of Nerve growth hormones, which handle the growth and repair of every brain cell. 

The Lion's Mane Mushroom is easy to combine with several other nootropic ingredients.

4. Vitamin B12

Vitamin B12 is an essential complex vitamin required by the brain to operate at maximum capacity while also delivering energy to the body. People can incorporate Vitamin B12 readily into their diet by eating foods that contain this vitamin, eliminating the need to stack the B12 supplement.

Additionally, B12 can be combined in nootropics stacks like the DHA, maritime pine bark, and caffeine. Lastly, people looking to improve their memory, attention span, mood, or looking to fix cognitive decline, vitamin B12 is one nootropic that should not be forgotten.

5. Citicoline

This essential nootropic is made of Choline and Cytidine, making citicoline a drug that improves how Choline and uridine are absorbed in the body. Once the Choline gets into the bloodstream, it is converted into phosphatidylcholine, which the body converts into acetylcholine. 

Citicoline also treats brain and cognitive decline, memory impairment, and improves focus.

6. L theanine and L tyrosine Amino acids

These two are essential amino acids. They are excellent for people looking to relieve stress and stay alert without having to deal with anxiety. The source of the L theanine essential amino acid can be traced to green tea. The L theanine amino acid combines well with nootropics like caffeine, and it can also be used for its antioxidant properties.

7. Rhodiola Rosea

The Rhodiola Rosea belongs to a group of extracts known as adaptogen extracts. It is commonly found in areas elevated from the rest of its surroundings in Europe during winter. 

People who use this extract recommend that it is excellent for improving mood, memory focus and also boasts of its anti-inflammatory functions. It combines well with DHA, Bacopa Monnieri, and tyrosine.

8. Maritime Pine Bark Extract

One essential antioxidant capable of protecting brain cells from damage is the maritime pine bark extract. This extract can induce the body to produce more nitric oxide, which in turn increases the flow and quantity of oxygenated blood in the body. It combines well with L Tyrosine and Citicoline.

9. Caffeine

Caffeine is perhaps the most popular nootropic in the world today. Many people take caffeine or caffeine substances to stay alert and increase productivity levels. It can be combined with several other nootropics, but caffeine intake should be used moderately because it can become addictive. 

The most popular source of Caffeine is the Coffee tree which is known for its highly stimulating effects. Caffeine containing substances like coffee should be used moderately as overuse can cause overdependence.

10. Huperzine A

Huperzine A, an extract from the Chinese moss plant, and like many of the other natural nootropic ingredients it has zero side effects when consumed. 

Numerous researches conducted on this extract shows that it is great for improving mood, cognitive and neurological function, and memory. The extract does this by preventing the breakdown of acetylcholine by acetylcholinesterase (AChE). So, it can be said to be an AChE inhibitor.

This extract is found in every packet of the potent Chinese Tianchi herb composed of several adaptogenic substances.

Types of Nootropics and Smart drugs

Over the counter Nootropics

This article's focus has been on only one type of nootropic, called over the counter nootropics. People do not need a doctor's prescription before using these cognitive enhancers. They include all the nootropics discussed till this point, they can either be synthetic or natural.

Prescription Nootropics

They include smart pills like

Modafinil- Recommended for people facing narcolepsy and drowsiness

Adderall -This cognitive enhancer is used to treat people with ADHD issues

Methylphenidate (Ritalin) - Used to treat narcolepsy and ADHD symptoms

Memantine (Axura) - Prescribed for people with Alzheimer's disease

The word prescription nootropics or the term smart pills or even cognitive enhancers has been used in several articles to classify this type of brain supplements. These prescription brain supplements should only be taken after getting clearance from a doctor. A doctor will prescribe the recommended drug and dosage.

These cognitive enhancers have several side effects and are dangerous if taken without a doctor's supervision. They also tend to compete with neurotransmitters in the body for dominance. Its use is also accompanied by several side effects including; high blood pressure, insomnia, blurry vision, and addiction.

All over the counter nootropics discussed at the beginning of the article with the exception of caffeine are known to have no side effects and tend to work in perfect synchrony with the body without competing with the body's neurotransmitters. So, if a person wants to improve overall cognitive function, they are the best nootropics to use.

However, it is recommended that a person still gets the green light from a doctor before using any form of cognitive enhancer or nootropics. Also, nootropic users should conduct extensive research before using any nootropic and always combine trusted nootropic stacks to deliver optimum results.


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